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analyse levels of identified proteins in a larger patient population as well as an animal model of the Fontan circulation.• You will use in vitro techniques and immunohistochemsitry on an animal model
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models. For the first time, this work will define PRDX1’s role as a modulator and redox relay hub in po-H₂O₂ signaling pathways. As PRDX1 is also emerging as a prognostic marker in solid tumors
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modelling and density functional theory calculations will be used to further increase our understanding of the photo-reduction mechanism. Correlating these theoretical insights with the structure and activity
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