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. The successful candidate will integrate multi-omic and immunological approaches, such as single-cell transcriptomics, proteomics, and tumor microenvironment profiling, and apply bioinformatic tools (e.g., R
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, genomics, or cell biology preferred. No prior experience required Skill in collecting, organizing, and analyzing data. Ability to recognize, analyze, and solve a variety of problems. Ability to exercise
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and in vivo models, including pancreatic islets. Develop and optimize cellular and animal models relevant to insulin resistance, beta-cell dysfunction, and related metabolic processes. Perform biomarker
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on human stem cell manufacturing, polymer-based biomaterials, and drug delivery. The projects will involve the fabrication of polymeric biomaterials in diverse presentations such as nanofibers, hydrogels
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rely on mouse models (knockout mice, conditional knockout mice, transgenic mice, PDX mice) and primary cell culture and cell line models (2D/3D organoids). Applicants must be willing to work with mice
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mouse models of immune dysregulation and/or malignant hematopoiesis; Drug screening, flow cytometry and microscopy, CRISPR screening and human cell line models. Additional duties will include: Contribute
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cell RNA sequencing, chromatin conformation assays, and the integration of these approaches. The studies involved will have a focus on cancer and neurodegeneration genomics. The postdoctoral associate
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vascular surgery, molecular biology and cell biology. - Conduct independent and collaborative research projects in limb ischemia, immunology and other diseases. - Design and implement experiments, analyze
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in basic molecular and cell biology techniques including mammaliam cell culture Must have experience with CRISPR and shRNA technology Must have some experience working with vertebrate animal models
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: Experience working with mice (especially models of heart failure or cancer), Experience with mammalian cell culture, protein expression, flow cytometry, tissue sectioning, and immunofluorescence, cardiac