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to survive antibiotic exposure without classical resistance. Our lab (boecklab.com ) has developed a large-scale live-cell imaging platform that tracks hundreds of millions of bacteria during antibiotic
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anatomy of the central nervous system. Work will involve both patient samples and experiments with live animals. Experimental methods include molecular and cell biology, flow cytometry, histology and
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, including the use of CRISPR-engineered cancer cell lines and metastatic models. In addition, the project integrates high-throughput metabolic profiling of genetic perturbations, computational data analysis
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is essential. Perform in vivo mouse studies using CRISPR-engineered cancer cell lines Design, perform, and analyse in vivo CRISPR pooled screens Perform high throughput metabolomics profiling using a
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strong interest in and commitment to animal experimentation is essential. Perform in vivo mouse studies using CRISPR-engineered cancer cell lines Design, perform, and analyse in vivo CRISPR pooled screens