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proteomic analyses often obscure the intricate cellular and molecular variations within this complex environment. Single-cell proteomics (SCP) offers a novel approach to dissect this heterogeneity by
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together world-class researchers from various fields, including neurophysiology, computational neuroscience, auditory cognition, genetics and genomics, cell biology and gene therapy. It is located in
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, and molecular evolution. The researcher will work within an international team to understand the evolution of integrons and other hyper-mobile regions in genomes. The focus will be on functional
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signal conditioning inside a Li-ion battery cell. In the new field of the Reference Electrode (RE) insertion inside the Li-ion cells, the PostDoc will focus on the pre-conditioning electronics necessary
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Postdoctoral position: Developing a human lymphoid organ-on-chip to evaluate candidate mRNA vaccines
the formation of activated CD4+ T cell/B cell clusters, were recapitulated in the LO chip. Further, cells within the chip were competent at capturing and expressing mRNA vectored by lipid nanoparticles, enabling
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(erasers: FTO, ALKBH5, etc.) and m6A-binding proteins (readers: YTHDF1, YTHDC2, etc.).m6A methylation can regulate the expression of oncogenes and control cell differentiation, proliferation and migration
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mutant and transgenic reporter lines in zebrafish and mouse Participate in all the metabolomic and singe cell transcriptomic aspects of the study, from sample preparation to data analysis Perform
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of brain and other mouse tissues.•Animal experimentation, including injections, perfusion, etc.•Molecular and cellular biology experimentation (e.g., PCR, Immunoblotting, cell culture)•Maintenance
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model of the synapse between the inner hair cell and auditory nerve: Long-term adaptation with power-law dynamics,” J. Acoust. Soc. Am., vol. 126, no. 5, pp. 2390–2412, Nov. 2009, doi: 10.1121/1.3238250
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Pasteur and aims at understanding hearing from both a fundamental and clinical perspective. It combines various approaches from genetics and cell biology to biophysics and from human cognition and