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technologies, microfabrication and microfluidics. This collaboration spans multiple institutions and international partners, combining strengths in research, translation and commercialisation. Key
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assembly and disassembly. The project combines cell-free expression, microfluidics, and fluorescence microscopy to build and characterize condensate systems that switch engineered functions on and off in
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characterization of high-quality mRNAs encoding for the antigenic peptides; 2) Use of microfluidic mixing to produce size-defined LNPs; 3) Set up of the strategies for the CuAAC functionalization of LNPs with alkyne
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decades of research, the interactions between multiple salt types during crystallization—both in bulk and under confinement—remain poorly understood. This PhD project offers an exciting opportunity
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. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations. Be Bold
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stress, e.g. through mechanical agitation or by applying shear forces in microfluidic devices, and will investigate how this impacts phase separation and aggregation of TDP-43, FUS or TAF15 in vitro. We