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the replication mechanisms of two selected bunyaviruses: Rift Valley fever virus (RVFV) and Hazara virus. Bunyaviruses are negative-sense RNA viruses with significant implications for public health and agriculture
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of the main features of cancer cells. DNA repair and the cell cycle arrest are protective mechanisms that prevent development of the genome instability. The tumor suppressor p53 plays a central role in
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Brno University of Technology, Central European Institute of Technology | Czech | about 2 months ago
: Fast force volume SPM data interpretation for nano-mechanical and electrical analysis with known uncertainty The main objective of the work is to develop fast data processing methods for processing force
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Project description Genome instability is one of the main features of cancer cells. DNA repair and the cell cycle arrest are protective mechanisms that prevent development of the genome instability
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significantly decreased food intake in mice, and lowered body weight of obese mice after chronic application, pointing to their blood-to brain transport. PhD project will explore the mechanisms involved in
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investigate specific instances in animals, where the molecular machinery of RNA silencing acquired unique adaptations to support specific functions of RNA silencing. Of particular focus will be adaptations
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of mobile elements. In contrast, euphalic forms exchange genetic information and allow the expansion of mobile elements in the genome. The main mechanism controlling mobile elements in the genome is the piRNA
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Dishevelled internal affairs in Wnt signaling Nucleic Acids Sensing Ribosome Assembly Mechanisms Deciphering the Argonaute Loading Mechanisms in RNA-Silencing Pathways More information about CEITEC PhD School
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tumorigenesis Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis The mechanisms of signalling pathways deregulation in acute myeloid
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on previous research of the group and investigate specific instances in animals, where the molecular machinery of RNA silencing acquired unique adaptations to support specific functions of RNA silencing