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mechanisms. The research fellow will focus on mass spectrometry based proteomics investigations of human heart samples in combination with experimental studies in iPSC derived cardiomyocytes. We are seeking a
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mechanisms regulating metabolic fuel homeostasis, with a particular focus on the brain’s role in metabolic regulation. We integrate human genetics, single-cell multiomics, and advanced model systems
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associations involve non-coding variants that lie within gene regulatory elements — enhancers or promoters. However, a lack of precise tools for the accurate assessment of regulatory activities, especially
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regulatory mechanisms that define how cell types and tissues emerge. The project is highly interdisciplinary and will include primarily experimental work (i.e., single cell method development, high throughput
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, including analysing the conditions and mechanisms that contribute to tipping points characterised by significant tempo-shifts in both decline of old technologies and adoption of new solutions. WP3 addresses