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Finite Element Model of the Larva Body: Utilise existing Drosophila larva CT-scan data to segment components such as the cuticle, muscles, and mouth hook. Implement finite element simulations within
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physiological human colon model, combining patient-derived colonic organoids with organ-on-chip (OoC) and enabling to modulate the key gut environmental cues: mechanical stimulation (peristalsis and shear stress
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with host receptors. Complementary biophysical and functional assays will be employed to correlate structure with adhesion mechanisms, providing insights into how bacterial pili assemble, extend, and
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