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. The candidate will join a multi-disciplinary team focusing on the development of new bioactive molecules targeting major signaling pathways in allergy, inflammation and cancer. Main targets are stress
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pathways in allergy, inflammation and cancer. Main targets are stress kinases vital for immune reactions, metabolic control and immune checkpoint modulation in cancer therapy. The working place of
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plasticity at the atomic level. At the center of this regulation lies PGC-1α, a transcriptional co-activator and master regulator of metabolic processes. PGC-1α dysfunction has been linked to obesity, diabetes
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to enhance the recovery of healthy hematopoiesis after chemotherapeutic damage in the context of hematopoietic malignancies. In this project, the candidate will work with human primary cells and perform cell