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there is no consistent evidence yet of increased cancer incidence [2]. It is therefore crucial to better understand the molecular responses to low dose IR (LDR) in order to improve the assessment of cancer
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differences or random direction stochastic approximations, offer general-purpose strategies that only rely on function evaluations. While conceptually simple, zeroth-order methods tend to scale poorly with
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objective function (eg, approximation error). A key question is to devise an algorithm that organizes the operators into a sequence, such that the best operators (low cost and high benefits) are performed
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