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and accepted to the PhD program at Stockholm University. Project description Project title: “Deep learning modeling of spatial biology data for expression profile-based drug repurposing”. A new exciting
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the molecular level. While structural predictions using deep learning methods like AlphaFold have revolutionized our understanding of sequence dependent molecular structure, we currently have much more limited
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will use machine learning methods to develop affinity ligands. These methods have been transformative for protein design, allowing generation of novel proteins which can suit a precise need. In this 4
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, structural biology, and NMR spectroscopy. The successful candidates will become a part of an international multidisciplinary environment and will receive ample opportunities for learning, collaboration and
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of MSI advances our understanding of complex brain processes. The prospective PhD candidate collects brain MSI data and develops novel machine learning methods in connection to generative models such as
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. We care about creating a positive, respectful, and stimulating environment, valuing communication and collaboration and a workplace that promotes learning and development for all. We are committed
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of small cryptic plasmids in the development and spread of antibiotic resistance, and ii) Use machine learning tools to examine the complex interplay between bacterial hosts, various plasmids and resistance
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) biological knowledge about GRNs from bioinformatics and system biology, (b) graph theory and topological data analysis for network modeling from mathematics, and (c) robust machine learning (ML) and GenAI from
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information. The techniques include image registration, segmentation, and regression/classification, often include deep learning-base implementations. Together with experts in epidemiology, genetic, and multi
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well as the clinical activities at the Karolinska University Hospital, unique access to international expertise in machine learning, state-of-the-art imaging, diverse patient cohorts, and relevant computational