Postdoctoral Fellow - Drug Development for Leukemia and Cancer

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The laboratory of Dr. Le Xuan Truong Nguyen in the Department of Hematological Malignancies and Translational Sciences is seeking highly motivated and innovative Postdoctoral Fellow. This is an excellent opportunity to join a well-established team and lead projects that culminate in publications in high-impact journals.

Our research focuses on drug development, uncovering basic mechanisms, and identifying novel therapeutic targets in leukemogenesis and solid tumors. Specifically, we study genetic and epigenetic biomarkers with prognostic value in acute myeloid leukemia (AML) and other solid cancers. Our work emphasizes therapeutic candidates targeting mitochondrial vulnerabilities, including nucleoside analogs, small GTPase inhibitors, natural plant extracts, and immunotherapies.

As a successful candidate you will:

·         Lead projects by designing and performing experimental procedures

·         Manage data, analyze, and report findings

·         Write scientific papers and grants

·         Work with PI and other team members to perform experiments in vitro and in vivo

·         Utilize the following in vitro skills (not limited to but including):

o   Aseptic techniques, cell culture, western blot, RNA/DNA extraction, protein extraction, RT-qPCR, seahorse, northern blot, bacterial transformation, cloning, lentivirus production, etc.

·         Utilize the following in vivo skills (not limited to but including):

o   Basic routes of administration (oral gavage, intraperitoneal, retro-orbital, subcutaneous, intra-venous injections), blood collection, organ harvesting (spleen, bone marrow, liver, etc.)

Your qualifications should include:

·         Ph.D. or M.D. in a relevant field.

·         Preferred experience in molecular signaling, cancer biology, leukemia research, and extensive murine studies.

·         Experience in immunology is an advantage.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here

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