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Summary:
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Details
Posted: 17-Apr-25
Location: Stony Brook, New York
Type: Full-time
Categories:
Staff/Administrative
Internal Number: 2501273
Job Description
Required Qualifications: (as evidenced by an attached resume)
* Doctoral degree (or foreign equivalent) in Molecular Biology, Cell Biology, Genetics, or a closely related field.
* Demonstrated experience in designing and conducting molecular and cellular biology experiments, as well as genetics-based research, with strong data interpretation skills.
* Experience with CRISPR screen and CRISPRi.
Preferred Qualifications:
* Extensive experience with CRISPR screen and CRISPRi.
* Strong publication record, including first-author papers in peer-reviewed journals.
* Expertise in molecular genomic techniques (e.g., PCR, qPCR, Western blotting, ChIP-seq, RNA-seq data analysis).
* Hands-on experience with mammalian cell culture.
* Experience in grant writing.
* Excellent communication skills (both written and oral) and clarity of thought in scientific discussions.
Brief Description of Duties:
The Postdoctoral Associate will assist the Principal Investigator, Dr. Fei Chen in the Department of Pathology and Stony Brook Cancer Center . We are seeking a highly motivated and skilled scientist with expertise in CRISPR screen and CRISPR interference (CRISPRi) to join our research team. The successful candidate will play a key role in investigating the epigenetic and genetic regulation of human cancers related to environmental and occupational exposures (e.g., mineral dust, carcinogenic metals, and chemical carcinogens).
Our lab has extensive expertise in metabolic and epigenetic reprogramming, malignant transformation, environmental microbiome interactions, and cancer stem-like cell generation in response to arsenic exposure.
The selected candidate will utilize cutting-edge techniques such as CRISPR-Cas9 gene editing, CRISPRi, ChIP-seq, RNA-seq, epitranscriptomics, and quantitative metabolomics to explore these mechanisms further. This position offers an exciting opportunity to work in a dynamic and interdisciplinary research environment focused on mechanistic insights into cancer initiation and progression.
Key responsibilities:
* Conduct cutting-edge cancer research within the predetermined scope and methodology.
* Design and perform CRISPR-based genetic screens (CRISPR-Cas9, CRISPRi) to investigate gene regulatory networks in cancer biology.
* Collect, analyze, and interpret data, including literature review and applying specialized techniques in the field.
* Prepare manuscripts for publication in peer-reviewed journals and contribute to grant writing efforts.
* Maintain the laboratory, including equipment upkeep and ordering supplies as needed.
* Present research findings at scientific conferences and meetings.
* Ensure compliance with Stony Brook University's research policies and procedures.
Special Notes:
The Research Foundation of SUNY is a private educational corporation. Employment is subject to the Research Foundation policies and procedures, sponsor guidelines and the availability of funding. FLSA Exempt position, not eligible for the overtime provisions of the FLSA. Minimum salary threshold must be met to maintain FLSA exemption.
Interested candidates should submit their CV, cover letter, and contact information for references.
Visit The Office of Postdoctoral Affairs to learn more about our postdoctoral community.
Resume/CV and cover letter should be included with the online application.
Stony Brook University is committed to excellence in diversity and the creation of an inclusive learning, and working environment. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, familial status, sexual orientation, gender identity or expression, age, disability, genetic information, veteran status and all other protected classes under federal or state laws.
If you need a disability-related accommodation, please call the university Office of Equity and Access (OEA) at (631) 632-6280 or visit OEA .
In accordance with the Title II Crime Awareness and Security Act a copy of our crime statistics can be viewed here .
Visit our WHY WORK HERE page to learn about the total rewards we offer.
SUNY Research Foundation: A Great Place to Work.
The starting salary range (or hiring range) to be offered for this position is noted below, it represents SBU's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Job:Post Doctoral
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