Research Infrastructure Specialist for CRISPR Functional Genomics (CFG)

CRISPR Functional Genomics (CFG) is a core facility at Karolinska Institutet and a national SciLifeLab infrastructure. Operating within the SciLifeLab platform “Chemical Biology and Genome Engineering”, CFG's mission is to support the Swedish research community in designing, executing, and interpreting large-scale CRISPR-based functional genomic screens and precision gene-editing experiments.

You will join a small, dynamic team as a Research Infrastructure Specialist. Your primary task will be to design and execute CRISPR-Cas projects in collaboration with facility clients. This includes performing precision gene editing in cell lines and conducting massively parallel genetic perturbations in a pooled format (pooled CRISPR screens). You will contribute to the development and implementation of cutting-edge CRISPR-based technologies and apply them in close partnership with clients. While your main focus will be on planning, designing, executing, and reporting experimental lab work, you will also support the management and operations of the unit.

To be eligible for employment as a Research Infrastructure Specialist at CFG, the applicant must:

• Hold a doctorate in a related field
• Possess technological and methodological expertise in relevant areas
• Be proficient in standard mammalian cell culture techniques
• Be fluent in English, both spoken and written 

The assessment criteria form part of the overall evaluation of the applicant’s qualifications. All criteria will be considered, but they should not individually be seen as strict requirements.

• Experience with viral delivery tools, molecular cloning techniques, flow cytometry (including cell sorting), next-generation sequencing
• Expertise in bioinformatics, including analysis of complex datasets and statistical methods
• Ability to demonstrate independent scientific thinking
• Strong enthusiasm for laboratory work
• Interest in creative method development and technical innovation
• A service-oriented mindset, with a primary focus on delivering high-quality datasets
• Proven ability to manage multiple projects in parallel, maintain meticulous documentation, and efficiently coordinate projects
• Strong interpersonal and communication skills 

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

Karolinska Institutet is one of the world's leading medical universities. As part of the Department of Medical Biochemistry and Biophysics, CFG offers a collaborative, dynamic, and friendly work environment housed in one of Europe’s most modern research facilities. Our clients’ projects span diverse areas of molecular cell biology, from basic cell biology and molecular medicine (cancer, neurodegenerative disease, infectious disease) to model organisms such as fish and insects.

CFG actively encourages personal and professional growth through access to courses and conferences. If you thrive in an academic environment, excel in laboratory work, but prefer to avoid publication pressure, CFG is the right fit for you.

This position is initially limited to one year. After this period, it is anticipated that the role will be advertised as a permanent position, for which the current holder is encouraged to apply.

Location: Biomedicum, Solna

Karolinska Institutet Research Infrastructure
SciLifeLab CRISPR Functional Genomics
New Career Path for Research Infrastructure Specialists

Your application should preferably be in English, but you may also apply in Swedish.An application must contain the following documents: PhD certificate, resumé, qualifications  presented in accordance with  Karolinska Institutet's qualifications portfolio for research infrastructure specialist. The application must also include a cover letter detailing why you are a strong match for the position.

The deadline for application is 2025-02-28.

The application is to be submitted through the Varbi recruitment system.