13 Feb 2025
Job Information
- Organisation/Company
Josep Carreras Leukaemia Research Institute (IJC)- Research Field
Medical sciences » Cancer research- Researcher Profile
Other Profession- Positions
Master Positions- Country
Spain- Application Deadline
28 Feb 2025 - 23:59 (Europe/Madrid)- Type of Contract
Temporary- Job Status
Full-time- Is the job funded through the EU Research Framework Programme?
Other EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer researchcenter dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced exponential growth.
The IJC is also part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC) Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII).
The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting-edge scientific and technological facilities, as well as complementary community services. The IJC has six locations integrated into reference hospitals: Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings.
The Josep Carreras Leukemia Research Institute Can Ruti is looking for a Lab Assistant Technician for the Cancer Metabolism group led by Dr. Lucas Pontel.
RESEARCH DESCRIPTION
Cancer is a major global health concern and understanding its underlying mechanisms is essential for developing effective treatments. Cancer cells undergo genetic and epigenetic changes, activating oncogenes and silencing tumor suppressor genes. These malignant cells also exhibit metabolic reprogramming for obtaining energy and nutrients differently than normal cells, granting them a growth advantage. To sustain this uncontrolled growth, cancer cells depend on robust antioxidant defenses, primarily provided by abundant nucleophilic molecules such as glutathione (GSH).
This project is focused on investigating and harnessing the functions of cellular nucleophilic metabolites, such as glutathione and cysteine, in the protection of the cancer genome and in the maintenance of the epigenome in cancer cells. Our endeavor involves the implementation of comprehensive genome-wide omics methodologies, including pooled CRISPR/screens within cellular models representative Acute Myeloid Leukemia (AML). Through this research, we aim to pioneer novel therapeutic strategies that trigger cell death in leukemic cells by precisely targeting metabolic pathways integral to defense mechanisms against detrimental metabolites.
For further information please contact lpontel@carrerasresearch.org
This contract is part of the project PID2022-136694NB-I00 funded by MCIN/AEI/10.13039/501100011033/ EDRF ‘A way to make Europe’, UE.
Where to apply
- Website
- https://careers.carrerasresearch.org/jobs/5553660-vac_13_2025-lab-assistant-tec…
Requirements
- Research Field
- Medical sciences » Cancer research
- Education Level
- Master Degree or equivalent
Skills/Qualifications
WHAT WE NEED
General skills
- Committed scientist with a competitive scientific record and experience in biology, biomedicine or related discipline.
- A high level of motivation and interest in biomedical research.
- Good communication skills.
Technical skills
- Degree in Biology or Biochemistry (or related field).
- MSc in Biology or Biochemistry (or related field).
- A high-level of motivation and interest
- Experience in molecular biology and cellular biology.
- High level of collaborative and communicative skills.
- High level of English speaking and writing skills (required). Spanish (helpful).
Specific Requirements
MAIN RESPONSIBILITIES
- Establish and maintain cellular models relevant for the aim of the project.
- Apply cell biology and molecular biology techniques to characterize the cellular models.
- Contribute to carry out CRISPR/Cas9 genome-wide screenings.
- Assist in lab organization tasks like inventory tracking, reagent preparation, and supply ordering.
- Collect and record experimental data, ensuring meticulous record-keeping and data quality.
- Engage in literature reviews to stay updated on relevant advancements.
- Collaborate effectively with the research team, contributing to lab meetings and discussions.
- Seize opportunities for skill development and scientific growth.
- Research Field
- Medical sciences » Cancer research
Internal Application form(s) needed
HR-01-01_JOB OFFER_VAC_13_2025_Lab Assistant.pdf
English
(212.58 KB - PDF)
Download
Additional Information
Benefits
WHAT WE OFFER
- 6 months trainee contract, with possibility of a 6-month extension.
- Start date: March 2025.
- A salary that with commensurate your qualifications.
- The stimulating environment of the IJC and its scientific network.
- Support for applications to eligible fellowships for pursue a PhD career.
Selection process
DEADLINE FOR APPLICATIONS
Please submit your application by 28th of February.
- Website for additional job details
https://www.carrerasresearch.org/es/investigacion/metabolismo-del-cancer
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Josep Carreras Leukaemia Research Institute (IJC)
- Country
- Europe
- State/Province
- Barcelona
- City
- Badalona
- Postal Code
- 08916
- Street
- Ctra de Can Ruti, Camí de les Escoles s/n
Contact
- State/Province
BARCELONA- City
Badalona- Website
http://www.carrerasresearch.org/en- Street
Ctra de Can Ruti, Camí de les Escoles s/n- Postal Code
08916
rrhh@carrerasresearch.org
STATUS: EXPIRED
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