One (1) Postdoctoral Researcher Position [Ref # PAR-0736]

10 Mar 2025
Job Information

Organisation/Company

Foundation for Research and Technology-Hellas

Department

Institute of Molecular Biology and Biotechnology

Research Field

Biological sciences

Researcher Profile

First Stage Researcher (R1)

Positions

Postdoc Positions

Country

Greece

Application Deadline

20 Mar 2025 - 13:00 (Europe/Athens)

Type of Contract

Temporary

Job Status

Part-time

Hours Per Week

20

Offer Starting Date

1 Jun 2025

Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The research group of Genome (In)stability and Mammalian Physiology (https://www.garinislab.gr/ ) under the Hevolution Foundation Geroscience Research Opportunities program (Project ID HF-GRO-23-119921), entitled “Targeting genome stability as root cause of aging” (Program Coordinator Prof. George Garinis) invites applications for one (1) postdoctoral researcher position.

About the lab

The Garinis lab investigates the impact of DNA damage on mammalian physiology during aging and its causative role in the premature onset of age-related diseases. We are using genetically engineered mouse models that carry inborn defects in Nucleotide Excision Repair and/or transcription as well as mice that carry tagged versions of proteins involved in DNA repair and/or transcription in combination with high-throughput, biochemical, molecular and cellular biology methods. This approach allows us to understand how mammalian cells exploit their natural defense strategies to counteract DNA damage-driven pathologies and prolong healthspan.

 

About the project: 

DNA damage constantly occurs and requires a range of DNA repair systems to maintain genome integrity. While the role of impaired DNA repair and DNA damage accumulation in causing age-related diseases have been intensely investigated, improving overall DNA repair capacities have remained elusive. Our recent discovery of the DREAM complex as a master regulator of DNA repair capacities has revealed a mechanism that could enhance overall genome stability. This research program focuses on uncovering the mechanisms of DNA repair gene regulation, exploring the fitness costs of enhanced somatic DNA repair and establishing in vivo how augmented DNA repair through DREAM inhibition could extend healthspan in mammals. 

 

Job Description: 

A highly motivated and experienced postdoctoral research scientist will participate in the project titled “Targeting Genome Stability as the Root Cause of Aging”, focusing on addressing the evolutionary trade-off of somatic DNA repair capacities and on investigating DREAM dysfunction in the DNA damage response in mice. The successful candidate should hold a BSc, MSc and PhD in Biology, Medicine, Life Sciences or related fields, and prior documented experience in molecular/cellular biology methods, imaging techniques, extracellular vesicles isolation and modification approaches and mouse genetics. Candidates with previous laboratory experience in the aging, DNA damage and repair research fields will be prioritized. Prior working  experience in biochemistry assays will be highly appreciated. Presentation, communication, collaboration, excellent scientific authoring and project management skills are pluses. S(he) should also have a strong publication record in peer reviewed journals in related research fields and fluency in English (written and oral). 

Where to apply

E-mail

par0736@imbb.forth.gr

Requirements

Research Field

Biological sciences

Education Level

Bachelor Degree or equivalent

Research Field

Biological sciences

Education Level

Master Degree or equivalent

Research Field

Biological sciences

Education Level

PhD or equivalent

Skills/Qualifications

Required qualifications: 

• B.Sc. degree in Biology, Life Sciences or related fields
• M.Sc. in Biology or related fields
• PhD title in Biology, Medicine, Life Sciences or related fields
• More than 3 years’ experience in molecular/cellular biology methods, imaging techniques, extracellular vesicles isolation and modification approaches and mouse genetics
• Laboratory experience in aging, DNA damage and repair research fields
• High-quality scientific publications in peer-reviewed journals on related research fields
• Certified oral and written skills in English language

 

Desired qualifications: 

• Prior experience in biochemistry assays
• Experience in participating and managing research programs

 

 

Evaluation criteria

Maximum score

1.

B.Sc. degree in Biology, Life Sciences or related fields

Yes/No

2.

M.Sc. in Biology or related fields

Yes/No

3.

PhD title in Biology, Medicine, Life Sciences or related fields

Yes/No

4.

Experience in molecular/cellular biology methods, imaging techniques, extracellular vesicles isolation and modification approaches and mouse genetics (≤5 years = 10 points, >5 years = 20 points)

20

5.

Laboratory experience in biochemistry assays (<1 year = 5 points, , ≥1 year = 10 points)

10

6.

Laboratory experience in aging, DNA damage and repair research fields (<5 years = 10 points, ≥5 years = 20 points)

15

7.

Oral and written skills in the English language (Β1 = 7 points, Β2 = 8 points, C1 = 9 points, C2 = 10 points)

10

8.

High-quality research publications on relevant scientific fields (≤2 publications = 5 points, 3-5 publications = 10 points, ≥6 publications = 15 points)

15

9.

Experience in participating and managing research programs (<12 months = 5 points, ≥12 months = 10 points)

10

10.

Interview (for the shortlisted candidates >65/80 points)*

20

Total score

100

 

*The shortlisted candidates will be invited for an interview. The evaluation criteria for the interview are: 

1. Perception - Judgement

2. Presentation and scientific authoring skills

3. Communication and collaboration skills

Languages

ENGLISH

Level

Excellent

Internal Application form(s) needed
Application form-en_0.pdf
English
(498.8 KB - PDF)
Download
Additional Information
Benefits

Contract Duration: 12 months with the possibility of extension according to the project needs

Total budget: 1.140,00 € monthly cost (incl. tax and social security), part-time employment contract 

Envisaged starting date: June 1st, 2025

Application submission: Interested applicants should submit their application electronically by March 20, 2025 @ 13:00 (Greece time)

Eligibility criteria

1. Application Form (see below) 

2. CV 

3. The names and contact details of two referees

4. Scanned copies of academic titles

5. Scanned copies proving all the qualifications

 

 

 

Submission of applications:  par0736@imbb.forth.gr  

Selection process

Evaluation procedure

Applications will be evaluated by a three-member evaluation committee. In case of interview procedure, applicants will be invited to participate in person or teleconference.

In case of titles and qualifications awarded by foreign Higher Education Institutions, the provisions of the Law 55/2023 (article 36) and 4957/2022 (article 304) are implemented.

The results of the selection will be announced on the website of IMBB-FORTH. Applicants have the right to appeal the selection decision, by addressing their written objection to the IMBB secretariat within five days since the results announcement on the web. Objections are submitted in one of the following ways: in person, by an authorized person, by post, by courier. They also have the right to access (a) the files of the applicants as well as (b) the table of applicants’ scores (ranking of applicants results). All the above information related to the selection procedure will be available at the secretariat of IMBB-FORTH in line with the Hellenic Data Protection Authority. Access to personal data of co- applicants  shall be limited to personal data (and relevant data) and supporting documents which have been the basis of the evaluation of the applicants for the specific post(s). Prior to the announcement of the personal data and/or documents of the co- applicants to the applicant, FORTH will inform the data subjects in an appropriate way.

The selected applicants will be notified personally regarding the success of his/her application and will be requested to submit certified copies of his/her degrees. If the submitted documents do not agree with the original application, the applicant will be dismissed. 

Additional comments

GDPR Disclaimer

FORTH is compliant with all legal procedures for the processing of personal data as defined by the Regulation EU/2016/679 on the protection of natural persons with regard to the processing of personal data. FORTH processes the personal data and relevant supporting documents that applicants have submitted. Processing of that data is carried out exclusively for the needs and purposes of this specific call. Such data shall not be transmitted to or communicated to any third party unless required by law. 

FORTH retains the above data up to the announcement of the final results of the call, unless further process and reservation is required by law or for purposes of exercise, enforcement, prosecution of certain one’s legitimate legal rights’ as defined in the Regulation EU/2016/679 and/or in national law. Under the Regulation EU/2016/679, applicants have the rights to be informed about their personal data, access to, rectification and erasure, restrictions of process and objection to as provided by applicable regulation and national laws. Applicants have the right to file a complaint to the national Data Protection Authority. For any further information regarding exercise of personal data protection rights, applicants may contact the Data Protection Officer at FORTH at dpo@admin.forth.gr .

Applicants have the right to withdraw your application and consent for the processing of personal data at any time. In this case, FORTH shall destroy such documents and/or supporting documents submitted and shall delete the related personal data.

Work Location(s)

Number of offers available

1

Company/Institute

IMBB

Country

Greece

Geofield

Contact

City

Heraklion

Website

http://www.imbb.forth.gr

Street

Vassilika Vouton

Postal Code

70013

STATUS: EXPIRED

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