5 Mar 2025
Job Information
- Organisation/Company
CNRS- Department
Institut Fresnel- Research Field
Computer science » Modelling tools- Researcher Profile
Recognised Researcher (R2)- Positions
Postdoc Positions- Country
France- Application Deadline
1 Apr 2025 - 00:00 (Europe/Paris)- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
35- Offer Starting Date
1 May 2025- Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Diffuse optics and multiphysics modeling for photodynamic therapy (PDT) of pancreatic cancer
Pancreatic cancer (PDAC) remains a major therapeutic challenge. Survival of PDAC patients has improved little over the past 50 years, underscoring the urgent need to develop new therapeutic approaches.
Photodynamic therapy (PDT) is emerging as a promising strategy for treating this type of cancer. Our interdisciplinary project aims to deepen understanding of the interactions between light and photoactivatable compounds to design targeted and optimized therapeutic treatment.
With the aim of guiding compound selection, optimizing treatment and proposing real-time therapy monitoring methods, we propose to develop a digital platform comprising: i) integration of organ morphology
(digital twin) and physical properties (optical, over a wide range of wavelengths, and mechanical), as well as those of the PSs developed; ii) implementation of propagation models for the various excitation sources used (from X-ray to near-IR, as well as ultrasound) and their interactions with tissues and PSs; iii) formalize and implement a method for optimizing the delivered dose (source distribution); iii) study the sensitivity of non-invasive probing techniques (diffuse optical or photoacoustic tomography) for monitoring these therapies.
Where to apply
- Website
- https://emploi.cnrs.fr/Offres/CDD/UMR7249-ANASOA-008
Requirements
- Research Field
- Computer science » Modelling tools
- Education Level
- PhD or equivalent
Skills/Qualifications
PhD in physics, applied mathematics, signal and image processing, digital imaging.
Specific Requirements
The candidate will work in a multidisciplinary environment.
- Languages
- ENGLISH
- Level
- Good
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- CNRS Institut Fresnel
- Country
- France
- Geofield
Contact
- City
Marseille- Website
http://www.fresnel.fr/spip- Street
Av Escadrille Normandie Niemen- Postal Code
13397
STATUS: EXPIRED
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