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neurons. Using a combination of high resolution live cell fluorescent imaging, electrochemistry and patch clamp electrophysiology, we recently discovered that activation of GLP-1Rs promotes the formation
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molecular biosciences backgrounds. The PhD will use pharmacology techniques, synthesis of complex molecules, cell biology, molecular biology assays, immunological staining of cancer cells and imaging. Please
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(Casson lab, https://www.sheffield.ac.uk/biosciences/people/academic-staff/stuart-casson) to develop the first comprehensive picture of chloroplast replication. In addition to opening up a new dimension of
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proteomics approaches and a variety of imaging techniques, including high-throughput, confocal and live cell imaging. Please apply for this project using this link: https://www.sheffield.ac.uk/postgraduate/phd
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vivo, fluorescent imaging, you will carefully examine the cell biology of immune-damaged cell interactions at these sites of damage. This careful characterisation will further inform and develop our
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to evaluate, develop and enhance the performance of prototype water quality monitoring systems. Use experimental testing results to consider the accuracy, reliability, robustness and maintenance requirements
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ECM preparation/generation Essential Application/interview Experience in fixed and live cell imaging Essential Application/interview Experience in Zebrafish xenograft cancer models Essential Application
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question in the fruit fly Drosophila. We study ultrafast morphodynamic adaptation in photoreceptor synapses to light changes using a range of methods, such as insect visual neuroscience/behaviour, image
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hypothesises that FIS1 regulates MLCS dynamics during hypoxia to coordinate mitochondrial remodelling, lysosomal reorganisation and cell survival. Three aims will be pursued using live/Fixed-cell imaging and
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large and vibrant team present within the Hearing Research group at Sheffield. The project will primarily involve using 2-photon imaging and AAV-gene delivery applied to a wide range of transgenic mice