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this research project, state-of-the-art techniques will be employed including multi-spectral imaging, methylome analyses, RNA-Seq at single-cell and bulk levels, cell culture as well as bioinformatics analyses
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behavioral assays in the animal models Immunohistochemical analysis of neuronal, astroglial and microglial markers in zebrafish and mouse brain samples In vivo imaging of specific brain cells in the transgenic
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. Experience in working with animal models, transcriptomics (long read, single cell), multi-parameter flow cytometry, molecular biology and fluorescence imaging will be preferred. We offer an interdisciplinary
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applications for a postdoctoral position to study the impact of nutritional state on brain function and brain energy use. For our investigations, we use cutting-edge techniques—including multiphoton imaging
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), Opn4 and Opn5, as photoreceptors not directly involved in image-forming vision has opened up for non-visual opsin studies. Our recent publication, using GFP reporter mice, provides evidence of early
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operate. Our approach We combine biochemical reconstitution, live-cell imaging, multi-scale structural biology, and omics technologies to uncover how the nuclear envelope functions as an intelligent
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activity will be academic research in association with a faculty member or team. The appointee will be responsible for preparing samples for X-ray and electron microscopy (EM) imaging (e.g., animal
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physics, applied mathematics, machine learning, bioinformatics, biophysics, spectroscopy, image processing, ecological modeling, molecular biology, plant physiology, marine biology or an interest in gaining
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opportunity to explore an essential question:- how does chromatin move and behave to control genes? To do so, you will lead an exciting HFSP-funded collaboration to apply single molecule imaging and genomics
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research is based on large and high-dimensional datasets across multiple modalities, including molecular, clinical and histopathology imaging data. Our computational pathology research is based