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and its plasticity. The project will be carried out by applying “all optical physiology” methods, i.e. a combination of calcium imaging with optogenetics, in freely behaving animals in Paolo Medini’s
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experiments using magnetogenetics to selectively control neurons and astrocytes in Alzheimer’s disease models, in vitro and in vivo . Perform in vivo two-photon imaging, electrophysiology, and behavioral tests
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of neural activity will be used in conjunction with advanced imaging methods and behavioural assays to investigate how signals beginning in the retina and transmitted through different visual pathways
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imaging. A successful postdoctoral candidate should have a Ph.D. in the relevant field with a strong background in LC-MS/MS. Some bioinformatics expertise is preferred but not required. More details about
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, molecular biology and biochemistry, immunofluorescence, super-resolution microscopy, calcium imaging, and surgical procedures. Performs other duties as assigned. Qualifications PhD or MD in Physiology or a
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content imaging, multi electrode array technology or reprogramming of somatic cells into pluripotency is necessary. Experience in computational image analysis and aging research is a strong plus. A
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If you have extended experience in imaging and imaging analysis from two- and three-dimension (3D) cell culture and your aspiration is to be at the forefront of system biology and single-cell
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hands-on experience in tissue handling, histology, microscopy, and spatial transcriptomics. Experience with the computational analysis of NGS- or imaging-based spatial transcriptomics and single-cell
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. The lab is well-equipped: BioRad ChemiDoc MP gel imager, SpectraMax iD3 microplate reader, Dynamic light scattering instrument, Waters HPLC-MS, Waters prep-HPLC, ÄKTA oligonucleotide synthesizer, CLASS II
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. Successful applicants will work together as part of an international team of experts at four sites to apply cutting-edge approaches in high-resolution, single-molecule imaging; single-cell Ribo-seq and spatial