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), live-cell imaging, and transcriptomic analyses. Laboratory work will involve optimizing protocols to convert patient-derived skin cells into neurons (iNeurons). New AONs will be screened through reporter
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of translation is crucial for controlling protein levels and guiding development. In the Ruijtenberg lab, we study these mechanisms using a combination of genome-wide sequencing and single-molecule imaging
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, including trans-differentiation of fibroblasts into neurons (iNeurons), development and screening of antisense oligonucleotides (AONs), live-cell imaging, and transcriptomic analyses. Laboratory work will
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lengthy processing times associated with sequencing. This PhD project aims to develop innovative artificial intelligence (AI) methodologies by integrating histopathology images and RNA sequencing data
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through a self-learning chip prototype, improving performance and durability in automotive applications. Specifically, this PhD project focuses on memristive materials as electronic realizations
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. Partnering with Toyota and Demcon TSST, SMIP will showcase this innovation through a self-learning chip prototype, improving performance and durability in automotive applications. Specifically, this PhD
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) Good communication skills in English Ability to work efficiently, both independently as well as in a team Previous experience in the fields of soft matter or biophysics, quantitative image analysis and
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) Good communication skills in English Ability to work efficiently, both independently as well as in a team Previous experience in the fields of soft matter or biophysics, quantitative image analysis and
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or biophysics, quantitative image analysis and programming experience with Python are beneficial but not required. We particularly encourage women and candidates from other groups which are currently under
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important question to solve, as DNA damage-stalled RNA polymerase causes bigger problems for the cells than the actual DNA damage itself. In this project we will use innovative single molecule imaging