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Field
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particular, we will use topology and shape optimisation methods to compute the optimal domain shapes that can stabilise solutions with desired/prescribed properties. We will use methods from inverse problems
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Start Date: Between 1 August 2026 and 1 July 2027 This project aims to frame hypersonic aerodynamics as a grand inverse problem. By combining modern state-of-the-art AI (foundation models, physics
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to the changing climate and extreme weather events, combined with pests and diseases. Phoma stem canker is a damaging disease of oilseed rape in the UK, causing annual yield losses worth £60-70M, despite the use
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health. Policymakers allocate limited testing and surveillance resources across different locations, aiming to maximise the information gained about disease prevalence and incidence. This project will
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Alzheimer’s, Parkinson’s, motor neuron disease, and related disorders. This project aims to understand the molecular mechanisms governing ESCRT dependent aggregate clearance versus extracellular vesicle (EV
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Cardiometabolic diseases (CVMD), such as heart disease and type 2 diabetes, represent a major global health burden and exhibit stark ethnic disparities. Current clinical prediction models, even
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Crohn’s Disease (CD) is a type of inflammatory bowel disease affecting > 120,000 people in the UK. It is a life-long condition often diagnosed in young adulthood. Symptoms include chronic abdominal
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characterize bioactive metabolites produced by bacteria associated with patients with inflammatory bowel disease (IBD) and colorectal cancer (CRC). Human-associated microbes produce metabolites that can have key
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biological problems. These may include: (1) Understanding how to 'glue' protein complexes together whose interactions are broken in diseases such as breast cancer. (2) Revealing how the most efficient light
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Primary supervisor - Dr Melanie Sloan Project: Flares of autoimmune rheumatic diseases, e.g. lupus, can be life and organ-threatening and significantly reduce quality of life. Identification of warning signs (“prodromes”) of impending flares, including type and progression of symptoms in flares,...