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regulation of nuclear xenobiotic receptors, (2) the mechanism of selective modulation of highly homologous drug-metabolizing enzymes. We are taking a hypothesis-driven and technology-enabled multidisciplinary
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modulation of highly homologous drug-metabolizing enzymes. We are taking a hypothesis-driven and technology-enabled multidisciplinary approach to develop chemical probes and investigate biological mechanisms
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expected to conduct homologous overexpression, gene silencing, sequence analysis and contained phenotyping. Education A PhD in Molecular Biology, Genetics, Genomics, or a closely related field Requirement
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characterised homolog is the Cre-recombinase family. This project aims to establish a novel set of biochemical assays to study the Captain’s ability to bind DNA and the affinity for specific sequences and to test
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experimental studies of RecA family protein mediated homologous recombination in collaboration with groups in the Biology Department at Northeastern University and the IBPC in Paris. The collaboration uses a
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FWO-UGent funded bioinformatics postdocs: Unveiling the significance of gene loss in plant evolution
to analyze gene loss across diverse plant lineages and their evolutionary consequences. To this end, the initial focus will be developing a novel genomic approach integrating homolog identification and
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of Molecular Cell Biology) at the University of Leicester for a BBSRC funded project focused on investigation of non-homologous end joining DNA double stand break repair mechanism in Mycobacterium tuberculosis
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of the applicant, the project will involve a combination of both in vitro techniques, such as cloning (both standard and knock-in/knock-out via homologous recombination), expression and (membrane) protein
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related to protein homology modeling, ligand docking and drug design to develop the next generation of safer anesthetics. Specifically, this individual will initially be an integral developer of a large