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execute experiments and contribute conceptually to the overall research programme. The post-holder should hold, or be close to completion of, a PhD/DPhil in biochemistry, molecular/cell biology or genetics
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to identify underlying genetic mechanisms. Whilst new technologies promise improved diagnoses and treatments, less attention has been directed towards the needs of, and support for, those affected by
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maintenance and resistance to chemo, radio and immuno-therapy, using genetic barcoding and clonal lineage tracing and single-cell and spatial omics. You will be a core member of the team, assisting with lab
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for Human Genetics in Oxford. The Tzima research group investigates the role of mechanotransduction in cardiovascular disease and the laboratory is at the cutting edge of developments in in vitro and in vivo
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new collaborations within the centre. You must hold a PhD (or near completion) in statistical genetics, functional genomics, computational biology, or a related field together with proficiency in
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background in mathematics, statistics, population genetics, phylogenetics, epidemiological modelling, or machine learning. Highly motivated candidates with some, but not all, of the skills requested will be
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work closely with lab members but with a focus on EV-associated fungal proteins. They will assist in protocol and technique development and use reverse genetics for functional analysis of EV candidates
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motility apparatus through single molecule fluorescence imaging approaches. Underpinning genetic and biochemical experiments will also be required. The project will build on our recent work in this area
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world-leading researchers from Oxford, Harvard, and other premier institutions to develop innovative gene-silencing and gene-editing technologies targeting the underlying causes of genetic heart diseases
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. This is a full-time appointment on a fixed-term contract for two years. The post-holder will be based at the Centre for Human Genetics, Old Road Campus, Oxford. Applications for this vacancy are to be made