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metabolic syndrome. Leveraging multiomics, mouse genetics, hiPS cells, and electrophysiology, the lab works on molecular mechanism of cardiometabolic oncology. For more information on Dr. Wang’s lab please
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progression once in post to £48,149 Grade: 7 Full Time, Fixed Term contract up to March 2028 Closing date: 13th August 2025 Background This research project aims to establish the theoretical and algorithmic
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algorithms, clinical decision support systems, and population health management platforms. Evaluate emerging technologies in clinical informatics and provide strategic recommendations for their adoption within
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of seed gene networks”. This project aims to use reverse genetics, cross-species complementation and single cell next-generation sequencing approaches to investigate how the gene networks that regulate
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toxicities, neuron-glia interactions, genetics and epigenetics will provide insights in identifying novel biomarkers and drug targets. Expand and improve skills: disease models based on genome-modified animals
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science into benefits for human health and the economy. About the role… The Genetic Mechanisms of Disease lab is a dynamic, supportive and highly collaborative research group which studies how common
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interest in methods development Experience in one or more of the following areas: algorithms development, transcriptome analysis, RNA modifications, statistics, machine learning, long read RNA-Sequencing
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the homeostasis of uridine and its role in metabolism, which provides a new angle for understanding the pathophysiology of obesity, diabetes and cancer. Work in the lab utilizes both genetically engineered mouse
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, prognosis, and predictive responses to chemotherapies and targeted drugs. 2. Study the genetic and epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone modifications, and non-coding RNAs
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multi-omics (PMIDs:33558758 [Nature Genetics 2021], 33514395 [Genome Biology 2021], and 33627474 [Genome Research 2021]), electronic health records (100 million electronic patient records, PMID