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. This is a full-time appointment on a fixed-term contract for two years. The post-holder will be based at the Centre for Human Genetics, Old Road Campus, Oxford. Applications for this vacancy are to be made
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gene-silencing and gene-editing technologies targeting the underlying causes of genetic heart diseases. The successful candidate will work closely with chemists, molecular biologists, and clinicians
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should have a MRes or PhD (or submitted at time of appointment) together with a strong academic track record, in a relevant area (e.g., Neuroscience, Medicine, Genetics, Mathematics, Engineering, Computer
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motility apparatus through single molecule fluorescence imaging approaches. Underpinning genetic and biochemical experiments will also be required. The project will build on our recent work in this area
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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling
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perform genetics, gene expression, and phenotyping aspects of the project. Key responsibilities: To understand and convey material of a specialist or highly technical nature to the team or group of people
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cell biology; cancer; cardiovascular; nutrition and diabetes; genetics; infection and immunology; imaging and biomedical engineering; transplantation immunology; pharmaceutical science; physiology and
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; biophysics and cell biology; cancer; cardiovascular; nutrition and diabetes; genetics; infection and immunology; imaging and biomedical engineering; transplantation immunology; pharmaceutical science
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purification, and recombinant DNA techniques. Experience of isolating proteins at native expression levels or from membranes, expertise in bacterial genetics, and expertise in quantitative fluorescence