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for young scientists and for their training, with many fruitful collaborations between teams. Mission The postdoctoral fellow will work on projects aiming to decipher the molecular mechanisms regulating
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populations to transmit ZIKV. In this collaborative project, we aim at characterizing the mechanisms underlying the transmission of Zika virus using an integrated approach that considers genetic variation in
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diseases such as nicotine addiction, schizophrenia or Alzheimer’s disease. Their architecture, allosteric mechanisms and pharmacology have been extensively studied over the last decades. However, the
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the team's previous work and develop a new high-throughput cell encapsulation instrument comprising a microfluidic card, a mechanical holder, pneumatic controllers, temperature control units, optical systems
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surveillance by the unfolded protein response (UPR), a major adaptive mechanism that lies at the core of cellular homeostasis and is responsible for cellular life-or-death decisions. The Inositol-requiring
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of mechanical forces within the neuroepithelium of the embryonic spinal cord, using organoid models derived from human induced pluripotent stem cells. iPSC cell culture CRISPR-Cas Imaging Image analysis
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not only flows from the auditory periphery to the central nervous system but also from the brain to the ear. As a result, efferent neuronal signals can modulate the mechanical properties of the cochlea
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area Travel to Nîmes (the model city) is to be expected. Knowledge of statistical analysis and modelling, analysis of complex networks, statistical mechanics Knowledge of R, Qgis, GIS software and
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cancer cells and in the macrophages within their tumor microenvironment. Our goal is to unravel the intricate mechanisms behind AIM2's recruitment to DNA-laden structures and explore the role of AIM2
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of immunomodulatory purinergic signaling in glioblastoma. Nat Commun 2022 - Touat M, Li YY, Boynton AN, …, Beroukhim R*, Bandopadhayay P*, Bielle F*, Ligon KL*. Mechanisms and therapeutic implications of hypermutation