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Field
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-bleaching of the fluorescent dyes involved, which ends the experiment prematurely, rendering many biological questions inaccessible. To bypass this limitation, our group has developed DyeCycling/FRET, where
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analytical tools such as small-angle X-ray scattering (SAXS) and fluorescence cross-correlation spectroscopy (FCCS). Our goal is to bring quantitative insights into how soft-matter systems self-assemble and
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fluorescence and NMR spectroscopy approaches to study intrinsically disordered proteins with the aim of understanding their conformational dynamics and interaction landscape and, thus, their way of function
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could take drugs right up to cancerous cells. This project offers hands-on training in cutting-edge techniques, including fluorescence microscopy, microfluidics, and biomolecular encapsulation. You will
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background in experimental microbiology and has laboratory experience in e.g., minimum inhibitory concentration (MIC) assays, molecular techniques (qPCR and dPCR), and fluorescence microscopy. You are expected
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), mouse models, fluorescence microscopy (confocal), genomics, epigenetics, cell biology and biochemistry techniques (e.g., RNA/ChIP-seq, mass spectrometry). Successful track record in conducting and driving
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diffraction tomography (ODT). The ODT will be used for imaging organoids and a correlative fluorescence microscopy must be integrated with the ODT. A close cooperation with COMBAT partners associated with WP 2
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resolving problems. Able to work independently and propose follow-up experiments. Desirable Qualifications: Experience with electrophysiology and/or two-photon or fluorescent imaging. Experience with
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of microfluidic cultivation platforms for co-cultures Live-cell microscopy (including fluorescence, phase contrast and time-lapse) for the analysis of cell interactions. Conducting cultivation experiments with
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to data analysis, lab maintenance, and collaborative research projects (Preferred) Conduct fluorescence imaging and analyze microscopic data Preferred Education & Experience The candidate should have a