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cryo-EM, cryo-ET, FIB milling, and biochemical methods to understand mechanisms of dynein-2 transport, building on recent advances in the group (NSMB 2017 PMID 28394326; NSMB 2019 PMID: 31451806; Cell
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of recombinant proteins as well as biochemical and biophysical characterisation methods are essential. You will possess sufficient knowledge and experience in mammalian cell culture and associated cell-based
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deep exploration of cancer precursors (precancers) to identify their molecular vulnerabilities and developing methods to intercept them. The alliance is led by Professor Sarah Blagden. You will be
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of novel strategies for neuronal analysis in health and disease and optimizing novel methods. The project is funded by My Name’5 Doddie Foundation, as part of their Catalyst Awards. Using iPSC-neurons, our
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training in psychiatry. The Head of Department is Professor Belinda Lennox. We are seeking a Postdoctoral Researcher who will be using molecular methods to explore the expression of voltage-gated calcium
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” approaches the lab has pioneered, including the use of TET-Assisted Pyridine-borane Sequencing (TAPS), an innovative sequencing method that allows the simultaneous detection of mutations and methylation
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at conferences and represent the research group at meetings. Having experience working with high-throughput sequencing methods, including bulk and single-cell RNA sequencing is desirable. Applications
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methods, including Mendelian randomisation, to identify candidate mechanisms linking circadian misalignment and sleep disturbances with cardiometabolic disease. The successful applicant will join an
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and realign how we measure and model populations by infusing new types of data, methods and unconventional approaches to tackle the most challenging demographic problems of our time. We are seeking a
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; • professional experience with force spectroscopy methods (e.g. optical tweezers, magnetic tweezers, or atomic force microscopy) is a plus; • interesting in developing a biochemistry skillset to enable