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Editing-based methods for the corrections of DNA mutations leading to cardiomyopathy. This work will be performed in primary cardiomyocytes from human iPS cells, human myocardial slices from patients and
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observational data, and compare the results with those from other emulators of similar datasets (e.g. Gaussian Process methods by the project lead). These results will inform the IPCC AR7, and adaptation and
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an interdisciplinary team of researchers as well as the Centre’s academic, lived-experience, and community partners. Additionally, you will work with researchers in the Centre’s Theory & Methods Hub and Communications
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more effective screening and therapy. The postholder will focus on developing and applying advanced computer vision and machine learning methods for multimodal imaging and real-time analysis in
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inherited conditions. In particular, the post-holder will develop CRISPR/Cas9- and Prime Editing-based methods for the corrections of DNA mutations leading to cardiomyopathy. This work will be performed in
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. Suggesting further appropriate methods and analyses. Writing manuscripts in to disseminate research findings. Present summaries of study updates at internal meetings and meetings with external collaborators
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well as statistical inferences on model outputs, for pre specified research hypotheses. Suggesting further appropriate methods and analyses. Writing manuscripts in to disseminate research findings. Present summaries
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-December 2025), the team developed playful, creative and inclusive methods for working with neurodivergent children and their families, and conducted the bulk of data collection. The primary role of the PDRA
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, creative and inclusive methods for working with neurodivergent children and their families, and conducted the bulk of data collection. The primary role of the PDRA is to support the design and UK-wide tour
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these projections with observational data, and compare the results with those from other emulators of similar datasets (e.g. Gaussian Process methods by the project lead). These results will inform the IPCC AR7, and