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. Zheng's lab works on problems at the interface of statistical, computational and biomedical sciences. The lab has developed methods to decipher gene cis-regulatory mechanisms from transcriptomics
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. In pursuit of these goals, they will leverage next-generation sequencing and advanced laboratory methods, including sterile tissue culture, proteomics, spatial proteomics/transcriptomics, and single
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backgrounds, a strong interest in understanding differential protein expression in in vivo samples and development of methods to further assess, identify and validate potential targets is required. Our
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single cell data through the application of best-practice bioinformatics workflows and the development of innovative methods as required. The position will require a highly motivated bioinformatician or
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/LINUX, are required. Experience in genome-wide methods, such as GWAS and post-GWAS analysis, and bioinformatic integration is desirable. Application address: Interested candidates should submit
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to demonstrate sufficient knowledge in developmental and stem cell biology and of research methods and techniques to work within established research programmes. Applicants will be able to design and undertake
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retroelements. Current work in the lab has identified several of these genomic parasites as cancer-specific elements. The focus is the creation of novel or alteration of existing gene function, through co-option
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protein biochemistry with technical expertise in protein expression and purification using mammalian or insect cell systems as well as basic molecular biology techniques. Experience in structural methods (X
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, particularly in prostate and colorectal cancer. We use various biochemical, molecular biological, and tumor biological methods, as well as digital spatial transcriptomics, confocal and fluorescence microscopy
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experience in cellular immunology and molecular biology are encouraged to apply. Technical experience in T-cell immunology and methods to examine immune responses (measurement of killing, cytokine production