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by exposure to potentially toxic elements. We investigate how environmental neurotoxicants contribute to oxidative stress, oligodendrocyte vulnerability, and the pathogenesis of demyelination. We also
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to the role of an Alzheimer’s disease susceptibility factor, CD33, in disease pathogenesis, as well as development of novel CD33-based therapeutics in this context (PMID:35940942). Transgenic models (PMID
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or related fields. Skills in mouse brain surgery, in vivo electrophysiology recordings and computer programming/analysis are an advantage. Applicants are required to send a cover letter detailing their
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Masters, and courses in the BSc and DVM programs. A large component of the research agenda within the Department of Biomedical Sciences is in translating fundamental research into practical applications
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to decipher the yet unknown function of this gene during neurodevelopment and central nervous system function. The project will focus on the analysis of neurodevelopment in different conditional KO mouse models
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effects of gestational cannabis exposure on offspring brain and behavioural development. The ideal applicant will have experience with single cell and/or spatial transcriptomic analysis as
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will involve studying the neural mechanisms underlying memory formation, social behavior, and societal structures in mice. By integrating brain activity data and behavioral analysis, we aim to uncover
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(immunohistochemistry and in situ hybridization) FACS and flow cytometry Proteomics analysis Computer image analysis We are looking for motivated candidates who hold a B.Sc. or MSc. in biology or related discipline. They
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, viral vector gene delivery optimization, and histological analysis. Experience with fiber photometry, optogenetics, or data analysis with Matlab/Python will be an advantage. The candidate should also
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linking sensory thalamus to motor cortex in the context of dexterous forelimb movements using viral tools, in vivo electrophysiology, chemogenetics, calcium imaging and movement analysis using deep learning