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to the design, control and validation of the secondary circuit of the device on the operational and biological level. The research engineer will build on proof of concept studies and previously conducted by
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allow researchers to explore alternative approaches. Target trial emulation is a structured framework to design observational studies that mimic randomized controlled trials, while reducing methodological
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. Randomized controlled trials (RCTs) underpin regulatory and clinical decision-making in healthcare, yet they are primarily designed to estimate average treatment effects within selected samples. This raises
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