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mission: to uncover how nutrient signaling pathways, particularly GATOR1-mTORC1, influence neurodevelopment and seizure formation in epilepsy and autism. Why Join Us? Work on cutting-edge projects exploring
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rare inherited childhood mitochondrial disease. It is typically caused by changes in a gene known as POLG, resulting in a severe epilepsy, developmental delay and liver failure. The epilepsy is very
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disorder (STXBP1-RD). Dr. Stamberger and Dr. Schoonjans are adult and pediatric neurologist respectively with a clinical focus on epilepsy and research focus on rare genetic epilepsy and neurodevelopmental
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-related disorder (STXBP1-RD). Dr. Stamberger and Dr. Schoonjans are adult and pediatric neurologist respectively with a clinical focus on epilepsy and research focus on rare genetic epilepsy and
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neurodevelopmental syndrome, STXBP1-related disorder (STXBP1-RD). Dr. Stamberger and Dr. Schoonjans are adult and pediatric neurologist respectively with a clinical focus on epilepsy and research focus on rare genetic
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of Neurophysiology). We are interested in the cellular and network mechanisms responsible for the generation of spike and wave discharges, the electrophysiological hallmark of absence epilepsy. The project is aimed
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on multiscale analysis of brain disorders with a focus on Parkinson’s and Alzheimer’s disease, and epilepsy by combining experimental and computational approaches. For a collaborative project within the Institute
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project at the CNNP Lab . The aim of ACORN is to understand the role of biological rhythms (chronobiology) in epilepsy and develop time-adaptive therapies. This project is funded by UKRI and is a
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. Building on this work, we seek to harness the power of this new tool to optimize its therapeutic use for a wide variety of conditions including epilepsy, neuropsychiatric disease, movement disorders, chronic
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October 2025. Project description Acute brain injury in the newborn is a major cause of death and lifelong disability, including cerebral palsy, intellectual deficits, epilepsy and autism spectrum disorders