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epidemiology. The models will describe the heterogeneous host population (naïve, naturally immunised or vaccinated) and several SARS-CoV-2 variants. The model will be informed by, and fitted to, exceptional data
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, which explores how plastic pollution may induce physiological and demographic changes in natural vector populations, potentially altering epidemiological dynamics and infection risk. Three key
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(epidemiological studies, pharmacodynamics, enzymatic activity measurement, etc.). The enzymatic study of dihydropteroate synthase (DHPS) will aim to determine the exact role of the various mutations in pfdhps in
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