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model of hematopoietic differentiation. We can now use this system alone or in combination with CRISPR perturbations of transcriptional regulators, using bulk and single cell readouts. Our experimental
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the ultimate goal to map and model human cell lineage dynamics across development, disease and aging at multiple levels of biological systems by integrating single-cell multi-omics and artificial intelligence
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into the brain with unprecedented efficiency and selectivity. Key Responsibilities Develop high-throughput screening cell-based BBB models. Utilize advanced molecular biology, proteomics and microscopy to study
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diabetes. The successful applicant will develop cell-based model systems such as human stem cell-derived beta cells, using single cell genomic read-outs, and will explore poorly understood genome regulatory