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to train an AI model that predicts the cis-regulatory code for synthetic genomes (i.e. for cell-free gene expression systems) and correlates the experimental conditions within the synthetic cell
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). The department’s laboratories are well equipped for molecular biology, cell biology, immunology, organoid culture, and omics-based analyses, offering an excellent research environment for a PhD candidate interested
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applications in regenerative biomedicine. Understanding the multiscale regulatory feedbacks between genes, proteins, cell behaviours, and tissue-scale mechanics is a major challenge. You will tackle
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of the mechanical properties of cell walls based on experiments and small-scale simulations developed elsewhere in theGreenTE consortium. Correct and improve your mathematical models in close collaboration with
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for treating damaged load-bearing cartilage by integrating clinically validated cell therapy with advanced biofabrication techniques. Our goal is to establish a single-stage treatment that enables efficient
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: minnaardgroup.nl). The project is entitled “selective modification of unprotected carbohydrates.” Carbohydrates (sugars) are ubiquitous in the living cell and fulfill essential roles. Carbohydrates are also used as
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the electrochemical active site and impact on transmembrane proton translocation. The project aims to develop new methods and devices routed on the chemistry of 2D materials and the functionalization of graphene
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of the technology associated to costs, durability and scale up. A potential option to address some of these challenges is enlarging the active cell area from the state-of-the-art of 100 cm², up to 1000 cm², as fewer
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, particularly under intermittent loads, remain a barrier for accelerated scale-up and deployment of these technologies. Thus, more than ever, it is vital to get in-operando information of cell behaviour beyond
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are looking for a PhD candidate to develop a hybrid physics-based and data-driven digital twin of an AEM cell. The goal of the digital twin will be to monitor the health and forecast the remaining useful life