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Background: The proposed project has emerged from a long-standing interest in the signalling and repair functions of the BRCA1 and PALB2 tumour suppressors. Specifically, we have been investigating
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heavily in people and infrastructure to enhance the experience of research students. The project also offers opportunities for collaboration with academic and industry partners in the fields of digital
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by BBSRC. References: Rashid et al. ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma. Jackstadt et al. Epithelial NOTCH signaling rewires the tumor microenvironment
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Project Outline Skeletal muscle undergoes progressive loss of mass and function during ageing, a process termed sarcopenia. This decline arises from reduced myogenesis and degeneration of existing
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, medicines, and even fuels. Their properties, like how stable or smooth they are, determine how well these products work. Studying emulsions also helps scientists understand fundamental processes in soft
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death. The role of NLR genes in these processes has been thoroughly described for plants and animals, but how they contribute to the fungal immune system is unexplored. Fungal NLR genes also show hugely
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mechanisms, namely the remodelling of membrane lipids. Lipid remodelling is a process whereby bacteria selectively modify their membrane lipid composition in response to a particular environmental stimulus
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, few people are trained in its operation. This PhD project will involve training on, and the further development of native mass spectrometry technology. The student will operate within the Advanced Mass
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-inflammation and psychiatric disorders (e.g. depression). The cellular processes underlying structural brain change include neurogenesis and gliogenesis, cell loss, changes in cell shape, synapse formation and
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-disciplinary PhD project aims to provide a clear picture of the landscape of battery manufacturing, waste and end-of-life processing. The project aims are to: Identify waste streams and energy requirements