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be validated in animal models. The candidate will contribute to (ii) differentiation of iPSCs into skeletal muscle cells and (ii) characterization of skeletal muscle according to differentiation
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and disadvantages). Literature review of computational fluid dynamics for viscoelastic fluids. Development of new elasticity models (generalization of integral and differential operators) and new
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perform the following tasks: Maintenance and differentiation of cell lines, as well as conducting experiments with cell lines and primary cultures; Application of Microscopy and Molecular Biology techniques
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systems (e.g. high-performance liquid chromatography (HPLC), particle size assessment (laser diffractometry (LD) and Dynamic Light Scattering (DLS)), release assays, differential scanning calorimetry (DSC
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differentiated neuronal cultures from induced pluripotent stem cells (iPSCs) and produce viral vectors for delivering CRISPR/Cas13 enzymes to engineer the transcriptome of the ATXN3 gene, aiming to alleviate