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substitution in the EGFRvIII peptide significantly increases survival in an animal model of glioblastoma by enhancing proteasomal processing. We also developed robust methods to detect a new class of non
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chain network analysis and geospatial modeling. The successful candidate will have strong data science skills, including experience working with large, complex data from varied sources, and machine
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flow cytometry. Our non-profit research administration organization, the Palo Alto Veterans Institute for Research (PAVIR), is located on the VA premises with a mission to facilitate research activities
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, with a focus on combination therapies that account for cell-cell interactions. Experimental model systems will include cancer cell lines, organoid/assembloid models, and clinical tumor samples. Projects
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) (link is external) leverages the current moment of revolutionary science and fosters deep omnidirectional collaboration across sectors, seeking to change the way that research in early childhood is
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-specific mechanisms underlying vascular diseases, ultimately to inform new treatment and prevention strategies. Other opportunities include use of animal model of disease to dissect the mechanism
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-specific networks driving the cellular responses. Given the complexity and dynamic state of signaling networks, the current understanding of their constituents and how they are spatiotemporally regulated in
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presentations). Evidence of their contributions to their current research communities. Track record of mentoring more junior scholars. Required Qualifications: PhD in computer science, electrical engineering
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particularly interested in leveraging the current technologies emerging in the stem cell field to develop more efficient and effective stem cell-based therapies for spinal cord injury, stroke, vascular dementia
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series of homology models of GABA receptors composed of variations in the available subunits. These models will be used to dock the few ligands available which are currently known to have GABAAR-slow