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similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly
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-family kinases and their control of the RAS/RAF/Map kinase pathway (Park et al., Nature 2019; Park et al., Nature Communications 2023), mutational activation of EGFR in lung cancer (Jia et al., Nature 2016
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relationship between protein quality control, stress response pathways and ageing. In addition, this project will be conducted in close collaboration with Professor David Gems. About the role You will be part of
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. Confidence working with the command line in a HPC environment. Applications from candidates with a background in mathematics or computer science with a keen interest in learning molecular neuroscience
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research on transcriptional and epigenetic mechanisms underlying the initiation, progression and immune control of human cancer, through onco-exaptation of endogenous retroviruses and other endogenous
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received transplants of islets enabling better blood glucose control without the need for insulin administration. Yet because there are not enough organ donors, new sources of insulin-producing cells
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projects will have to undergo a check versus national export, sanctions and security regulations. Candidates may be excluded based on these checks. Primary checkpoints are the Export Control regulation
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, interplays with the ubiquitin pathway, controls DNA repair, replication, sister chromatid cohesion and supports genome stability. Ubiquitin typically targets individual proteins and high selectivity is