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of our integrated, systematic, and multidisciplinary research program. Our efforts are directed at identifying and overcoming stromal barriers to treatment (including elevated interstitial pressures
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adenocarcinoma (PDA) pathogenesis. The murine models of distinct genetic subtypes of pancreas cancer that we have developed form the basis of our integrated, systematic, and multidisciplinary research program. Our
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induced neuropathology and develop strategies for viral eradication from central nervous system using a novel mouse model. Experience in HIV-1 biology and disease pathogenesis is helpful but not mandatory
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