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molecular mechanisms that cause the whole-body response to cancer. We employ pre-clinical and clinical research to develop and test new treatment strategies combining body reprogramming and anti-cancer
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discovery and chemical biology. Our lab is working to understand the molecular mechanisms leading to efficient elicitation of tumor vulnerability for potent cancer targeting. We develop Targeted Protein
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the transcriptional mechanisms of nuclear receptors in the context of brain development, innate behavior, and disease risk. Gonadal hormones such as estrogen and testosterone are the principal regulators of sex
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