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University, one of Europe’s leading biomedical institutions. This position focuses on unraveling the regulatory networks underlying dormancy and therapy resistance in acute myeloid leukemia (AML). Using
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of the anaphase-promoting complex (APC/C) and the degradation of cyclin B1. If cyclin B1 levels fall below a critical threshold, cells undergo mitotic slippage, entering G1 without proper chromosome segregation
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