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Postdoctoral position: Developing a human lymphoid organ-on-chip to evaluate candidate mRNA vaccines
the formation of activated CD4+ T cell/B cell clusters, were recapitulated in the LO chip. Further, cells within the chip were competent at capturing and expressing mRNA vectored by lipid nanoparticles, enabling
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transcriptomic analyses (RNA-sequencing, 10X genomics) and epigenetic signatures (DNA methylation, chromatin accessibility, ChIP-sequencing, and Hi-C conformation capture techniques) for the genes involved in
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