8 civil-engineering-soil-structure-interaction PhD positions at Heidelberg University
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assays to assess for intercellular interaction and migration, CRISPR-based perturbation-of-adhesion and synthetic lethality screening, drug synergy assays, and others. The PhD student will work closely
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cell culture Gene editing using CRISPR/Cas9 CRISPR screening Broad cell & molecular biology techniques Your profile Enthusiastic about discovery and translational research Master’s degree in Molecular
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of primary cardiomyocytes and analysis of contractility and calcium transients Establishment of in vivo disease models to test therapeutic efficacy of S100A1ct and other S100A1-derived peptides Interaction
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Perform ligand-receptor and network-based modeling of cell-cell interactions Communicate findings through presentations, publications, and consortium meetings Your profile MSc in Bioinformatics
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culture and molecular biology techniques. The project also comprises a substantial amount of in vivo work, which will be performed in collaboration with experienced senior researchers. Therefore, a strong
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RNA modifications and their associated enzymes using CRISPR-Cas9 knockouts in both primary healthy and malignant cells, as well as established cell culture models Conduct colony-forming unit (CFU
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. Your Profile Master degree (or similar) in molecular biology, biomedicine, biotechnology, bioinformatics or a related field Experience in molecular biology methods (e.g. PCR, NGS, cell culture) and/or
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of the tumor suppressor p53, which upregulates the cyclin-dependent kinase (CDK) inhibitor p21. In this project, we aim to investigate the crosstalk between mitotic timing and G1 arrest using engineered cell