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Postdoctoral position: Developing a human lymphoid organ-on-chip to evaluate candidate mRNA vaccines
. To address this issue, we developed a lymphoid organ-on-chip (LO chip) model based on a microfluidic chip seeded with human PBMC at high density within a 3D matrix. Perfusion of the SARS-CoV-2 Spike
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Université Paris-Saclay. Free shuttle buses and transit-pass discounts are provided for researchers who wish to live in downtown Paris. Hybrid work options (partially remote) are possible. This work will be
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transcriptomic analyses (RNA-sequencing, 10X genomics) and epigenetic signatures (DNA methylation, chromatin accessibility, ChIP-sequencing, and Hi-C conformation capture techniques) for the genes involved in
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. Acids Res., 2018, 46, e70. S. Porte et al., Proc. European Organ-On-Chips Society (EUROoCS), p. 342, Milano, Italy, 2024. Required work: - Extraction and selection of tumor cells from patient samples