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Summary The main focus of the Aras lab is to characterize the mitochondrian—nuclear cross talk and their contributions to breast cancer cell growth and metastasis. Techniques in molecular biology
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Summary The fellow will be involved in studies, which are aimed at understanding G protein-mediated signaling mechanisms underlying islet beta-cell function in health and diabetes. Specifically
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degradation (ERAD) machinery in health and disease, with a special focus on the regulation of liver homeostasis. The lab uses interdisciplinary state-of-the-art approaches, powered by cell type-specific mouse
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Summary The primary research focus is the role of cell adhesion and neuronal self-avoidance in the developing mouse retina, focusing on two families of cell adhesion molecules: the clustered
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excellent training and recent research experience in protein analysis and molecular/cellular biology or a closely related discipline. The research focus spans several disciplines from commercial insulin
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adipose tissue, muscle, liver and cancer cells (Cell Metabolism 22:852, 2015; J Pharmacol Exp Ther. 363:367, 2017; Mol Metab 7:57. 2017). 2) Analysis of cellular plasticity in adipose tissues. This project
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Summary We study cell division mechanisms using C. elegans as a model organism. Our main R01 funded project seeks to characterize novel functions of separase during cytokinesis. We use multiple
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medicinal chemistry to available cellular and animal models of PDand is geared towards achieving groundbreaking steps in the field. Among the research approaches to be investigated are gene therapy, exosome
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research work on G protein-mediated signaling mechanisms underlying islet beta-cell function in health and diabetes. Specifically, these investigations will assess roles of G proteins and their regulatory
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Summary A postdoctoral position is available in the laboratory of Paulo Caceres, Ph.D., at Henry Ford Health System to study mechanisms of epithelial polarity and cell-cell communication in