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Enhancers are crucial regulatory elements in the genome, controlling gene expression and playing a pivotal role in cellular differentiation and neurological disorders. Despite their importance
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. For example, we ignore exactly how cells produce most of it, how it is removed from the circulation, and how it could best be used as a diagnostic tool. This funded PhD studentship at the University of Exeter
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pluripotent stem cell-derived MNs to mimic TDP43 mislocalization without external stress. We've identified splicing errors in genes crucial for cytoskeletal integrity and neurotransmission. Our project will
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Project Summary: During type 1 diabetes progression, immune cells infiltrate the pancreatic islets leading to pancreatic beta-cell destruction. This process, in part, is driven through increased
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Statistical modelling for single-cell RNA sequencing data for crucial health applications Supervisors: Magdalena Strauss (Mathematics and Statistics), Akshay Bhinge (Clinical and Biomedical Sciences