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The Laboratory for Cellular Metabolism and Metabolic Regulation (Fendt Lab) is a young and dynamic team of researchers performing cutting edge cancer metabolism research with special focus on cancer
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project focusing on a long-standing and fascinating question : « what makes our brain cells human ? » (see our recent work : Hecker et al. Science 2025; Libé-Philippot et al. Cell 2023; Vanderhaeghen and
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developmental biology, cell biology and evolutionary biology. We like to implement novel omics technologies such as single cell approaches and chemical biology to help us answering our biological questions
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including fragmentomics, methylomics, etc). In addition, results will be compared and integrated with bulk and single-cell/spatial data obtained on matching tumor cells. About TOBI-lab The overarching goal
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question: « what makes our brain human ? » (Vanderhaeghen and Polleux, Nat. Rev. Neurosci. 2023). We combine cutting-edge approaches such as pluripotent stem cell models of human corticogenesis, human-mouse
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innovative research on how tissue-resident macrophages respond to pathological stimuli and influence brain homeostasis. Apply cutting-edge techniques including spectral flow cytometry, spatial and single-cell
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skills in R and/or python Experience with iPSC and/or cell culturing We offer As part of the VIB-UAntwerp Center for Molecular Neurology and VIB , the applicant will benefit from established
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high potential to suppress disease expression and/or progression. Your job You will work with a team of scientists interested in (1) mechanisms of neurodegeneration, (2) cellular determinants of disease
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. At our Center, researchers study the cellular mechanisms of health and disease in the central nervous system. The De Wit lab (Laboratory of Synapse Biology) at the VIB-KU Leuven Center for Brain & Disease
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for months, years, or even millennia. Our lab aims to resolve the molecular mechanisms behind this process, focusing on how promiscuous enzymes (un)intentionally transform cellular metabolites into degradation